CORONAVIRUS

EU Regulator Authorizes AstraZeneca Vaccine For All Adults

Jan 29, 2021, 11:48 PM
An NHS staff member prepares an AstraZeneca Covid-19 vaccination as over-eighty year olds receive t...
An NHS staff member prepares an AstraZeneca Covid-19 vaccination as over-eighty year olds receive their vaccinations on January 26, 2021 at Stithians Showground, near Truro, England. A further 32 vaccination centres are opening across England as the rollout programme continues to ramp up. The latest Government figures showed more than 6.3 million people across the UK have received their first dose of the vaccine with a record-breaking 491,970 being injected in a single day over the weekend. (Photo by Hugh Hastings/Getty Images)
(Photo by Hugh Hastings/Getty Images)

BERLIN (AP) — Regulators authorized AstraZeneca’s coronavirus vaccine for use in adults throughout the European Union on Friday, amid criticism the bloc is not moving fast enough to vaccinate its population.

The European Medicines Agency’s expert committee unanimously recommended the vaccine to be used in people 18 and over, although concerns had been raised this week that not enough data exist to prove it works in older people, and some countries indicated they may not give it to the elderly.

The shot is the third COVID-19 vaccine given the green light by the European Medicines Agency after ones by Pfizer and Moderna. The EMA’s decision requires final approval from the European Commission, a process that occurred swiftly with the other vaccines.

Hours later, the EU gave its backing for the vaccine’s use throughout its 27 nations.

“I expect the company to deliver the 400 million doses as agreed. We will keep on doing all we can to secure vaccines for Europeans, our neighbours & partners worldwide,” tweeted EU Commission President Ursula von der Leyen.

With trials showing about 60% efficacy, the vaccine appears to offer less protection than ones already authorized, but experts have said any vaccine with an efficacy rate of over 50% could help stop outbreaks.

The agency recommended the vaccine’s use by older people, despite limited data regarding its efficacy in people over 55, citing the immune responses seen and experience with other vaccines.

“At least some protection is expected,” Bruno Sepodes, of the EMA’s expert committee, said Friday at a briefing. He acknowledged that “the exact level of protection cannot be estimated for the time being.”

Many countries on the continent have been struggling to vaccinate people as quickly as Britain, Israel, the U.S. and elsewhere, and it was long hoped that the AstraZeneca shot would help speed things up at a time when countries face surging cases in a pandemic that has taken the lives of more than 400,000 people in the bloc.

The EU bet heavily on the shot, which is cheaper and easier to handle than some other vaccines, with orders for 300 million doses to be delivered after authorization and options for another 100 million doses.

“None of them is a magic wand on its own, but together they provide tools and options to prevent different aspects of the disease,” said Emer Cooke, the head of the EMA.

The AstraZeneca vaccine has been authorized for use in all adults in other countries, even though only 12% of the participants in its research were over 55 and they were enrolled later, so there hasn’t been enough time to get results.

EMA’s decision authorizes AstraZeneca’s vaccine to be used across the bloc, but individual countries can still decide how and to whom they will give the doses they receive.

Lithuania, for instance, will not use the vaccine in older people, the country’s deputy Health Minister Zivile Simonaityte said, according to the Baltic News Service. It was not clear, however, what age groups would be given the shot, but Simonaityte noted that trials in people 55 and over were not “comprehensive.”

Germany may follow a similar path. The country’s independent vaccine advisory committee recommended Friday that the shot only be given to people under 65. The final decision rests with the government, but it is likely to follow this advice.

Thomas Mertens, the head of the German advisory committee, said the general approval by EMA was “confusing” in light of the data provided by AstraZeneca but that he and his colleagues would gladly update their recommendation if further data comes in.

Mertens stressed that the German experts were mainly concerned about the clinical data provided by the company so far.

“The AstraZeneca study was a little more messy overall,” he said.

Julian Tang, a virologist at the University of Leicester, said the German decision to restrict the vaccine’s use to younger people meant more older people would be vulnerable to COVID-19 and that some would die unnecessarily.

“There’s a tremendous cost to this,” he said. “It means you have an extra vaccine that could be used to protect people that is going unused and more people will be at risk.”

Tang described the EMA’s authorization Friday as “the best decision in the current situation, where the EU is in desperate need of a usable vaccine.”

The agency assessed four trials in the U.K., Brazil and South Africa and said the research showed the vaccine proved to be about 60% effective by reducing the number of people who got sick. The trials have not yet shown whether the vaccine can stop disease transmission.

A separate study testing the AstraZeneca vaccine in the U.S. is still underway.

As the EU has struggled to roll out the vaccine, politicians have blamed supply problems, but other factors, like onerous paperwork and poor planning, have also played a role. The EU has particularly lashed out at AstraZeneca after the drugmaker said it would initially supply less vaccine than originally anticipated. Exacerbating concerns about supplies to the bloc, which is home to some 450 million people, Moderna told countries including Italy and Denmark the company would be delivering fewer vaccines than originally expected.

Spahn, the German health minister, said he understood many were waiting impatiently for the vaccine, but cautioned that “several hard weeks of vaccine shortage still lie before us.”

Two more vaccine makers also recently announced results, with Novavax saying this week that its shot appears 89% effective based on early findings and Johnson & Johnson saying its long-awaited single-shot vaccine was 66% effective at preventing moderate to severe illness. If those vaccines are eventually licensed, that could help alleviate the pressure on the world’s huge demand for the limited shots currently available.

The authorization of the AstraZeneca vaccine comes amid a bitter dispute between the drugmaker and the bloc after the company said it would sharply reduce initial deliveries from 80 million doses to 31 million. The EU also introduced tighter rules on exports of COVID-19 vaccines that could hit shipments to nations like the United Kingdom.

The AstraZeneca vaccine has already been authorized in more than 40 countries, including Britain, India, Argentina and Mexico. The World Health Organization is also reviewing it; a recommendation from the U.N. health agency would allow its purchase and distribution to developing countries from a global program known as COVAX.

—-

Cheng reported from Toronto. Associated Press writers Samuel Petrequin and Raf Casert in Brussels, Nicole Winfield in Rome, Danica Kirka in London, Angela Charlton and Alex Turnbull in Paris, and Jan M. Olsen in Copenhagen, Denmark, contributed.

KSL 5 TV Live

Top Stories

Coronavirus

FILE: Pfizer-BioNTech COVID-19 (left) and Moderna COVID-19 (right) vaccines are seen at a vaccinati...
Jed Boal

Despite reaching 5,000 deaths, Utah’s COVID-19 numbers are down

The director of the World Health Organization said yesterday about COVID-19, “the end is in sight,” even if we are not there yet.
10 days ago
FILE PHOTO (Photo by Al Bello/Getty Images)...
Associated Press

WHO: COVID end ‘in sight,’ deaths at lowest since March 2020

The head of the World Health Organization says the number of coronavirus deaths last week was the lowest reported number in the pandemic since March 2020, marking what could be a turning point in the years-long global outbreak.
10 days ago
A school classroom with chairs and desks...
Brooke Williams

Project to provide air purifiers in Utah K-12 classrooms

Cleaner air improves student performance, decreases COVID transmission and school absenteeism. New project provides air purifiers for classrooms in Utah.
11 days ago
SHANGHAI, CHINA - JULY 08: People walk by a closed store at a neighborhood designated as a medium-r...
Laura He, CNN Business

Zero- COVID-19 at what price? Chinese researchers are treading on sensitive ground

Authorities in Shanghai have denied a report by a leading Chinese real estate research firm that claimed more than a third of shops in a major mall had been shuttered because of strict COVID-19 curbs.
13 days ago
FILE: Pfizer-BioNTech COVID-19 (left) and Moderna COVID-19 (right) vaccines are seen at a vaccinati...
LAURA UNGAR AP Science Writer

Is COVID-19 winding down? Scientists say no

New booster shots have arrived and social distancing guidelines have eased but COVID-19 infections aren't going away anytime soon. Experts predict the scourge that's already lasted longer than the 1918 flu pandemic will linger far into the future as the virus continues to cause deaths and may well mutate or evolve into a new disease.
17 days ago
A teacher starts to reset up her classrooms at Freedom Preparatory Academy as they begin to prepare...
COLLIN BINKLEY, AP Education Writer

Reading, math scores fell sharply during pandemic, data show

A new national study finds math and reading scores for America's 9-year-old students fell sharply during the pandemic, underscoring the impact of two years of learning disruptions.
24 days ago

Sponsored Articles

young woman with stickers on laptop computer...
Les Olson

7 ways print marketing materials can boost your business

Custom print marketing materials are a great way to leave an impression on clients or customers. Read for a few ideas to spread the word about your product or company.
young woman throwing clothes to organize a walk in closet...
Lighting Design

How to organize your walk-in closet | 7 easy tips to streamline your storage today

Read our tips to learn how to organize your walk-in closet for more storage space. These seven easy tips can help you get the most out of your space.
Types of Computer Malware and Examples...
PC Laptops

5 Nasty Types of Computer Malware and Examples | Everything You Need to Know to Keep Your Computer and Family Safe

Here are the different types of computer malware and examples that could potentially infect your computer.
tips how to quit smoking...

7 Tips How to Quit Smoking | Quitting Smoking Might be One of the Hardest Things You Ever Do but Here’s Where You Can Start

Quitting smoking cigarettes can be incredibly difficult. Here are 7 tips how to quit smoking to help you on your quitting journey.
Photo: Storyblocks...
Blue Stakes of Utah 811

Blue Stakes of Utah 811: 5 Reasons To Call 811 Before You Dig When Working in Your Yard

Call before you dig. Even at home, you could end up with serious injuries or broken utilities just because you didn't call Blue Stakes of Utah 811.
Days of...
Days of '47 Rodeo

TRIVIA: How well do you know your rodeo? Take this quiz before you go to the Days of ’47!

The Utah Days of ’47 Rodeo presented by Zions Bank is a one-of-a-kind Gold Medal Rodeo being held July 20-23, 25 at 7:30 PM. The Days of ’47 Rodeo How well do you know your rodeo trivia? Take the quiz to test your know-all before heading out to the Days of ’47 Rodeo at the […]
EU Regulator Authorizes AstraZeneca Vaccine For All Adults